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The Research Assistant I will:
- Conduct bench-level experiments involving molecular biology and genomic techniques, including genotyping and sequencing using robotic liquid handlers, cell culture, and other laboratory experiments to follow up on genetic results.
- Prepare, handle, and track patient DNA samples for various genetics projects. Ensure sample quality for use in several high-throughput genetic analysis platforms.
- Play a role in developing and optimizing technologies and protocols crucial to project goals.
- Be involved in experimental and project planning and analysis of data. Participate in lab meetings to share results. Play a role in working with fellow laboratory staff to coordinate and plan experiments.
- Ensure that genetic data meets quality control metrics. Prepare and calculate graphical displays of these data.
- Analyze, document, and compile data. Report data to lab head and lab members in oral and written reports.
- Operate and maintain automated laboratory equipment critical to investigations, and prepare, order, and maintain stocks of necessary reagents, solutions and supplies.
To qualify, you must have:
- A Bachelor's degree in biology or related field.
- At least 1 year of experience in a molecular biology or genetics laboratory, preferably on an independent project, with familiarity with genomic methods.
- A familiarity with basic molecular biology or genotyping/sequencing techniques, and the operation of standard lab equipment.
- Excellent analytical and communication skills and the ability to interact professionally with all levels of staff and with external contacts in a dynamic collaborative environment.
- Excellent knowledge of computers.
- Excellent organization and time management skills and the ability to handle a variety of tasks simultaneously required.
- Familiarity with robotic liquid handlers or similar equipment a plus.
- Comfort with statistics or programming, strong plus.
You will join a multidisciplinary team of researchers focused on using genetics to understand the biology of human obesity, height, and other diseases and polygenic traits. You will perform laboratory experiments at BCH and also interact closely with teams at the Broad Institute of Harvard and MIT. Projects will involve the use of genomic and genetic methods to generate and analyze data, including from genotyping, DNA sequencing, and gene expression profiling, as well as experimental work to follow-up on genetic and genomic discoveries. Leadership roles will be available on projects as comfort levels with the methodologies increase. In the context of a small core facility, responsibilities will also include SNP genotyping, preparing samples for DNA sequencing, and interaction with local researchers to enable genotyping and sequencing projects from within the Harvard community, and ordering reagents. You will work with a program coordinator and the principal investigator to facilitate the general functioning of the lab and ideally transition into a more senior lab management role in the future. Must be independent and comfortable working on array of genetic and genomic projects at various stages and levels of involvement.
BCH is an Equal Opportunity / Affirmative Action Employer. Qualified applicants will receive consideration for employment without regard to their race, color, religion, national origin, sex, sexual orientation, gender identity, protected veteran status or disability.
Standard Hours Per Week: 40