Department: Medicine, Division of Infectious Diseases Work Schedule: Monday-Friday/37.5 hours
Under the general supervision of a faculty investigator in the Laboratory for Integrative NanoDiagnostics, the Research Specialist II is responsible for developing clinical antibody/protein assays on silicon microchips. The successful candidate will have an opportunity to work with a multidisciplinary team to develop a novel platform for performing point-of-care immunoassays.
The successful candidate will have a strong background in a chemistry-related field (such as Chemistry, Biochemistry, Clinical Chemistry), will be able to work independently and with a team, be proficient with statistical analysis (such as R and matlab), and must have excellent scientific communication skills, both written and oral. Follow established procedures and utilizes appropriate technique to conduct experiments associated with the development and optimization of silicon microchip-based clinical assays. Includes, but not limited to:
Perform benchscale assays to assist in the development of antibody/protein-based clinical assays and assist in experiments to transfer and optimize benchscale assays to run on silicon microchips.
Assist in performing antibody/protein-based assays on silicon microchips, which may involve sophisticated instrumentation such as optical and fluidic platforms.
Perform benchscale and on-chip assays using clinical specimens under BSL-2 conditions.
Operate basic laboratory equipment such as centrifuge, pH meter, analytical balance, scintillation counter, light and/or fluorescence microscope, microplate reader, plate washer and biological safety cabinet. This person may also utilize spectrophotometer, flow cytometer, benchtop clinical chemistry analyzer, and laboratory automation solutions/robotics.
Familiarity with basic laboratory techniques such as pipetting, buffer and reagent preparation, pH determination, spectrophotometric absorbance determination and fluorescence detection.
Maintains and makes necessary adjustments to equipment, e.g. calibrating, alignment. Prepares solutions, reagents, and stains following standard laboratory formulas and procedures. Along with the laboratory supervisor, works to develop and institute standard operating procedures.
Responsible for operation of lab computers for data entry and analysis. Maintain accurate data records and laboratory notebook.
This description is a general statement of required duties and responsibilities performed on a regular and continuous basis. It does not exclude other duties as assigned.
Bachelor's degree in biology, chemistry or related field. Two years laboratory experience performing relevant techniques. Master's degree, with related graduate research, may substitute for experience to the extent permitted by the JHU equivalency formula.
Special Knowledge, Skills, and Abilities: Proficiency in standard biochemistry and molecular biology experimental techniques. Proficiency in scientific communication, both written and verbal, to support video and teleconferences with overseas collaborators. May include brief international travel.
JHU Equivalency Formula: 30 undergraduate degree credits (semester hours) or 18 graduate degree credits may substitute for one year of experience. Additional related experience may substitute for required education on the same basis. For jobs where equivalency is permitted, up to two years of non-related college course work may be applied towards the total minimum education/experience required for the respective job.
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