The Rockefeller University seeks a Research Support Associate to join High Throughput Screening Resource Center. The Research Support Associate will be responsible for converting miniaturized cellular and biochemical assays into high throughput screens using automated liquid handling instruments and microplate detection systems. Responsibilities include programming, maintenance, and quality control, training scientists and technicians in setting-up screening assays and developing and using assays, providing assistance, training, and guidance to the HTSRC users in the operation and programming of lab instrumentation, particularly liquid handling instruments and fluorescent plate readers, and delivering formatted compound plates for single point concentrations and IC50 experiments for screening and S.A.R studies. The Research Support Associate will be responsible for storing, securing and delivering appropriately formatted compound libraries for HTS using automated systems, maintaining, upgrading and calibrating microplate readers, optical instruments and automated pipette workstations, procuring necessary repairs and service, working with vendors to troubleshoot instrument failures, and maintaining an appropriate inventory of laboratory supplies and safety infrastructure. Responsibilities also include data analysis, interpretation and maintenance of the HTS database and hard drives, planning and performing evaluations of new technologies and approaches, miniaturization and design of screening assays, and measuring affinity of small molecules using biophysical techniques. Will communicate with the Director, and the HTSRC scientists through detailed and comprehensive written reports and through accurate and timely verbal information.