The Rockefeller University seeks a Research Support Associate to join High Throughput Screening Resource Center. The Research Support Associate will be responsible for converting miniaturized cellular and biochemical assays into high throughput screens using automated liquid handling instruments and microplate detection systems. Responsibilities include programming, maintenance, and quality control, training scientists and technicians in setting-up screening assays and developing and using assays, providing assistance, training, and guidance to the HTSRC users in the operation and programming of lab instrumentation, particularly liquid handling instruments and fluorescent plate readers, and delivering formatted compound plates for single point concentrations and IC50 experiments for screening and S.A.R studies. The Research Support Associate will be responsible for storing, securing and delivering appropriately formatted compound libraries for HTS using automated systems, maintaining, upgrading and calibrating microplate readers, optical instruments and automated pipette workstations, procuring necessary repairs and service, working with vendors to troubleshoot instrument failures, and maintaining an appropriate inventory of laboratory supplies and safety infrastructure. Responsibilities also include data analysis, interpretation and maintenance of the HTS database and hard drives, planning and performing evaluations of new technologies and approaches, miniaturization and design of screening assays, and measuring affinity of small molecules using biophysical techniques. Will communicate with the Director, and the HTSRC scientists through detailed and comprehensive written reports and through accurate and timely verbal information.
Bachelor's degree in science required; educational emphasis in biology, chemistry, or equivalent preferred. A Master's degree, Ph.D. and/or industrial experience are viewed upon favorably. A minimum of four years of post-graduate experience and extensive expertise with an HTS-related technology required. Detailed knowledge of the operation of fluorescent microplate readers and other biophysical methods for measuring small molecule-receptor interactions necessary.
We offer an excellent benefits package, tuition reimbursement and a competitive salary. The Rockefeller University is located on Manhattan's Upper East Side, on a 15-acre campus, along the East River (www.rockefeller.edu/views.php).
The Rockefeller University is an Equal Opportunity Employer - Minorities/Women/Disabled/Veterans.
Click here to apply directly using The Rockefeller University website.
The Rockefeller University is a world-renowned center for research and graduate education in the biomedical sciences, chemistry, bioinformatics and physics. The university's 72 laboratories conduct both clinical and basic research and study a diverse range of biological and biomedical problems with the mission of improving the understanding of life for the benefit of humanity.