The Research Specialist B will work in the newly established High-Throughput Screening Core (HTSC) in the Perelman School of Medicine (PSOM). The primary mission of the core is to provide the PSOM community with high-throughput screening capabilities to identify genes or organic small molecule modulators of signaling pathways, cellular phenotypes, and protein function in models of human disease. He/she will work with the Technical Director of the core to design, optimize and validate biological assays in high-density formats (i.e. 384 well microtiter plates) that can be screened against libraries of FDA approved drugs and/or siRNAs. The Research Specialist will be expected to become proficient in mammalian cell-culture, and biochemical or cellular assays as they apply to high-throughput genetic/chemical screening. The candidate will be expected to operate and maintain automated laboratory robotic workstations related to high-throughput screening; prepare and manage libraries of siRNA, shRNA, cDNA, CRISPR and drug-like small molecule libraries for high-throughput screening; and analyze, interpret, and prepare reports of large data sets. Additional responsibilities will include maintaining articulate documentation of daily tasks and maintenance of the laboratory’s databases/logs and inventory (i.e. supplies, reagents, and equipment).
Penn has a long and proud tradition of intellectual rigor and pursuit of innovative knowledge, begun by Benjamin Franklin in 1740. That tradition lives today through the creativity, entrepreneurship, and engagement of our faculty, students, and staff. Academic life at Penn is unparalleled, with an undergraduate student body of 10,000 from every U.S. state and around the world. The entering class ...of 2015 is the most talented and diverse in Penn's history. Consistently ranked among the top 10 universities in the country, Penn welcomes an additional 10,000 students to our top-ranked graduate and professional schools.